Reference/DeleteRegKey

DeleteRegKey

[/ifempty] root_key subkey

Deletes a registry key. If /ifempty is specified, the registry key will only be deleted if it has no subkeys (otherwise, the whole registry tree will be removed). Valid values for root_key are listed under WriteRegStr. The error flag is set if the key could not be removed from the registry (or if it didn't exist to begin with).

DeleteRegKey HKLM "Software\My Company\My Software"
DeleteRegKey /ifempty HKLM "Software\A key that might have subkeys"